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Symbol Name ID |
Ctla4
cytotoxic T-lymphocyte-associated protein 4 MGI:88556 |
| Darker colors indicate more annotations |
| Human Phenotypes | Retinal hemorrhage |
Diffuse alveolar hemorrhage |
Localized pulmonary hemorrhage |
Conjunctivitis |
Keratoconjunctivitis sicca |
Pericarditis |
Abnormal cardiac ventricular function |
Orthostatic hypotension |
Hypertension |
Portal hypertension |
Raynaud phenomenon |
Arrhythmia |
Tachycardia |
Ventricular tachycardia |
Heart block |
Congestive heart failure |
Abnormal lymph node morphology |
Lymphadenopathy |
Splenomegaly |
Hepatosplenomegaly |
Erythema |
Facial erythema |
Dermatographic urticaria |
| Disease(s) Associated with CTLA4 | |||||||||||||||||||||||
| atopic dermatitis | |||||||||||||||||||||||
| Behcet's disease | |||||||||||||||||||||||
| graft-versus-host disease | |||||||||||||||||||||||
| granulomatosis with polyangiitis | |||||||||||||||||||||||
| Graves' disease | |||||||||||||||||||||||
| multiple myeloma | |||||||||||||||||||||||
| primary biliary cholangitis | |||||||||||||||||||||||
| sarcoidosis | |||||||||||||||||||||||
| Sjogren's syndrome | |||||||||||||||||||||||
| systemic lupus erythematosus |
| Mouse Phenotypes | enlarged heart |
vascular inflammation |
myocarditis |
|
| Availability | Mouse Genotype | |||
| Ctla4tm1Shr/Ctla4tm1Shr | ||||
| Ctla4tm1Saka/Ctla4tm1Saka Foxp3tm1(cre)Saka/Y (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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